Tadalista tablets work by overcoming the main reason that causes ED problems i.e. insufficient blood flow to the male organ. The primary agent of this generic medicine, Tadalafil, start its work as soon as it enters the bloodstream by inhibiting the enzyme, Phosphodiesterase type five (PDE5). A decrease in this natural enzyme causes a rise in the proportion of cGMP and nitric oxide in the body. These chemical compounds dilate the arteries and relax the penile muscles, hence increasing the blood flow in the erectile organ. A sufficient amount of blood lets the person achieve the desired erection when you go through sexual stimulation.